diff --git a/.gitignore b/.gitignore
index 833d4182..5b91bed7 100644
--- a/.gitignore
+++ b/.gitignore
@@ -13,6 +13,7 @@ setup.iss
 /setup/macos/Info.plist
 /setup/windows/build
 .venv
+/uv.lock
 
 # Translations
 /novelwriter/assets/i18n/*.qm
diff --git a/docs/requirements.txt b/docs/requirements.txt
deleted file mode 100644
index 767647e7..00000000
--- a/docs/requirements.txt
+++ /dev/null
@@ -1,8 +0,0 @@
-docutils>=0.17.1
-pygments>=2.7
-sphinx-book-theme
-sphinx-copybutton
-sphinx-design
-sphinx-favicon
-sphinx-intl
-sphinx>=5.0
diff --git a/requirements-all.txt b/requirements-all.txt
deleted file mode 100644
index d140ead6..00000000
--- a/requirements-all.txt
+++ /dev/null
@@ -1,5 +0,0 @@
--r requirements.txt
--r requirements-dev.txt
--r docs/requirements.txt
--r setup/requirements.txt
--r tests/requirements.txt
diff --git a/requirements-dev.txt b/requirements-dev.txt
deleted file mode 100644
index 794644e0..00000000
--- a/requirements-dev.txt
+++ /dev/null
@@ -1,4 +0,0 @@
-build
-isort
-pyright
-ruff
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index fa1cf957..00000000
--- a/requirements.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-pyqt6>=6.4
-pyenchant>=3.0.0
diff --git a/setup/make_pip.sh b/setup/make_pip.sh
index f7e82c65..9d3c61b2 100755
--- a/setup/make_pip.sh
+++ b/setup/make_pip.sh
@@ -10,8 +10,8 @@ echo ""
 echo " Building Dependencies"
 echo "================================================================================"
 echo ""
-python3 pkgutils.py build-assets
-python3 pkgutils.py icons optional
+uv run pkgutils.py build-assets
+uv run pkgutils.py icons optional
 
 echo ""
 echo " Building Packages"
diff --git a/setup/requirements.txt b/setup/requirements.txt
deleted file mode 100644
index 120a3f4f..00000000
--- a/setup/requirements.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-setuptools>=77.0.3
-twine
diff --git a/tests/requirements.txt b/tests/requirements.txt
deleted file mode 100644
index 39f96e3c..00000000
--- a/tests/requirements.txt
+++ /dev/null
@@ -1,5 +0,0 @@
-coverage>=7.2.0
-pytest-cov
-pytest-qt
-pytest-timeout
-pytest>=6.0.0